The main audience for this guide is practitioners who want to assess pedestrian and bicyclist risk. Some elements of the risk assessment methods in this guide are straightforward and should not pose significant difficulty for most practitioners, such as tabulating observed crashes from existing databases or collecting counts of pedestrians and bicyclists. Some analytic methods in this guide are more complex and may require specialized knowledge and skills, such as estimating expected crashes or estimating pedestrian and bicyclist exposure using a travel demand model. However, the process for assessing pedestrian and bicyclist risk in this guide provides flexibility, such that practitioners may select simpler methods that are consistent with their analysis capabilities and resources.